Fluid restriction reduces delayed hyponatremia and hospital readmissions after transsphenoidal surgery.

Restricting fluid to 1 L/d on discharge decreases rates of delayed hyponatremia and readmissions by 50%. Standardized patient education and POD 7 sodium testing decreases severity of hyponatremia but does not impact readmission rates. These protocols should be considered standard practice for patients undergoing transsphenoidal surgery.