The digital expression profile of BMP7, CDKN2C, HIST1H3G, and PKMYT1 genes improves high-grade cervical lesion detection in liquid-based cytology.

Rhafaela Lima Causin,Luciane Sussuchi da Silva,Leticia Ferro Leal,Júlio César Possati-Resende,Adriane Feijó Evangelista,Graziela Macedo Matsushita,Cristovam Scapulatempo-Neto,José Humberto Tavares Guerreiro Fregnani,Marco Antônio de Oliveira,Laura W Musselwhite,Márcia Maria Chiquitelli Marques,Rui Manuel Reis

Cancer cytopathology（2023）

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摘要

A gene expression profile that may be helpful in the identification of patients with CIN2+ was identified. This approach could be used together with currently used LBC in a clinical setting, allowing the identification of patients with high risk of CIN2+.

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关键词

biomarkers,cervical cancer,cervical intraepithelial neoplasia,gene expression,liquid-based cytology

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