The Transcriptomics of the Human Vein Transformation After Arteriovenous Fistula Anastomosis Uncovers Layer-Specific Remodeling and Hallmarks of Maturation Failure.

Laisel Martinez,Miguel G Rojas,Marwan Tabbara,Simone Pereira-Simon,Nieves Santos Falcon,Mohd Ahmar Rauf,Akshara Challa,Zachary M Zigmond,Anthony J Griswold,Juan C Duque,Roberta M Lassance-Soares,Omaida C Velazquez,Loay H Salman,Roberto I Vazquez-Padron

Kidney international reports（2023）

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摘要

This work delineates the molecular changes that characterize venous remodeling after AVF creation and those relevant to maturation failure. We provide an essential framework to streamline translational models and our search for antistenotic therapies.

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关键词

arteriovenous fistula,extracellular matrix,maturation,transcriptomics

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