Design of an Ante-enhancer with an Azone-Mimic Structure using Ionic Liquid.

Takeshi Oshizaka,Mao Hayakawa,Mayu Uesaka,Kota Yoshizawa,Tomoyo Kamei,Issei Takeuchi,Kenji Mori,Shoko Itakura,Hiroaki Todo,Kenji Sugibayashi

Pharmaceutical research（2023）

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摘要

These results suggest the usefulness of designing a skin penetration enhancer using ionic liquid technology. Further trials on the ionic liquid design with an Azone-mimic structure using other cations and anions may lead to the development of better ante-enhancers.

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关键词

ante-enhancer,ionic liquid,laurocapram,skin irritation,skin permeation

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