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COVID-19 in Patients with Chronic Lung Disease.

Jessica Fae Calver,Laura Fabbri, James May,R. Gisli Jenkins

Clinics in chest medicine(2023)

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Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus that causes an acute respiratory tract infection known as coronavirus disease 2019 (COVID-19). SARS-CoV-2 enters cells by binding the ACE2 receptor and coreceptors notably TMPRSS2 or Cathepsin L. Severe COVID-19 infection can lead to acute lung injury. Below we describe the current evidence of the impact of common chronic lung diseases (CLDs) on the development of COVID-19. The impact of treatment of CLD on COVID-19 and any risk of vaccination in patients with CLD are considered.
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Key words
Chronic lung disease&nbsp,Vaccination,Chronic lung disease,Asthma,COPD,Cystic fibrosis,Interstitial lung disease,Pulmonary arterial hypertension,COVID-19 susceptibility
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