Brain transcriptome-wide association study implicates novel risk genes underlying schizophrenia risk.

Chengcheng Zhang,Xiaojing Li,Liansheng Zhao,Wanjun Guo,Wei Deng,Qiang Wang,Xun Hu,Xiangdong Du,Pak Chung Sham,Xiongjian Luo,Tao Li

Psychological medicine（2023）

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摘要

Our findings identified novel SCZ risk genes and highlighted the importance of the TWS genes in frontal-limbic dysfunctions in SCZ, indicating possible therapeutic targets.

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关键词

GWAS,TWAS,eQTL,schizophrenia,white matter tract

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