Identification of telomere-related genes associated with aging-related molecular clusters and the construction of a diagnostic model in Alzheimer's disease based on a bioinformatic analysis.

Yang Ruan,Weichao Lv, Shuaiyu Li,Yuzhong Cheng,Duanyang Wang,Chaofeng Zhang,Kuniyoshi Shimizu

Computers in biology and medicine（2023）

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摘要

Our analyses revealed novel TRGs associated with aging clusters in AD patients and their immunological characteristics. We also developed a promising prediction model based on TRGs for assessing AD risk.

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关键词

Aging,Alzheimer's disease,Artificial neural networks,Immune infiltration,Machine learning,Molecular clusters,Prediction model,Telomere

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