Circular RNA Ubiquitin-associated Protein 2 Silencing Suppresses Bladder Cancer Progression by Downregulating DNA Topoisomerase 2-alpha Through Sponging miR-496.

Yang Fu,Kun Liu,Lun Zhao,Xi Jiang,Tianwei Wang

European urology open science（2023）

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摘要

Circular RNA ubiquitin-associated protein 2 (circUBAP2) was found to be associated with poor prognosis in bladder cancer (BC). Knockdown of circUBAP2 might suppress BC growth, invasion, migration, and aerobic glycolysis, indicating that it may be a new target for the development of molecular targeted therapy for BC.

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关键词

Aerobic glycolysis,Bladder cancer,Circular RNA ubiquitin-associated protein 2,DNA topoisomerase 2-alpha,miR-496

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