Catastrophic antiphospholipid syndrome accompanied by complement regulatory gene mutation.

Serim Pul,İbrahim Gökçe,Ece Demirci Bodur, Serçin Güven,Neslihan Çiçek,Mehtap Sak,Özde Nisa Türkkan,Deniz Filinte,Cemile Pehlivanoğlu,Betül Sözeri,Harika Alpay

The Turkish journal of pediatrics（2023）

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摘要

The clinical course of complement mediated CAPS tends to be worse. Complement system dysregulation should be investigated in all CAPS patients, and eculizumab treatment should be kept in mind if detected.

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关键词

antiphospholipid antibody syndrome,complement activation,human complement factor H-related protein,thrombotic microangiopathy

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