Supplementary Figure Legends from Evolutionary Action Score of <i>TP53</i> Coding Variants Is Predictive of Platinum Response in Head and Neck Cancer Patients

Supplementary Figure Legends. Expression of p53 target genes is impaired following cisplatin treatment in HNSCC harboring mutant TP53; TP53 knockdown illustrates both loss and gain of function in vitro in HNSCC cells;Effect of cisplatin therapy on tumor growth and survival in an orthotopic nude mouse model of oral tongue cancer harboring TP53 mutations presented as area under the growth curve (AUC).