Supplementary Figures S1-S6 from Warfarin Blocks Gas6-Mediated Axl Activation Required for Pancreatic Cancer Epithelial Plasticity and Metastasis

Amanda Kirane, Kathleen F. Ludwig,Noah Sorrelle, Gry Haaland, Tone Sandal, Renate Ranaweera,Jason E. Toombs, Miao Wang,Sean P. Dineen,David Micklem,Michael T. Dellinger,James B. Lorens,Rolf A. Brekken

crossref（2023）

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摘要

Supplementary Figures S1-S6. Axl is required for the growth of Mia PaCa-2 tumors (S1); Characterization of 10C9 (S2); Warfarin inhibits autocrine activation of Axl in pancreatic tumor cells (S3); In vivo warfarin effects (S4); Maintenance of mesenchymal phenotype is Axl dependent and inhibited by warfarin (S5); Acquisition of Axl expression sensitizes Capan-EMT cells to warfarin (S6).

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