Supplementary Figure 5 from Stress-Response Protein RBM3 Attenuates the Stem-like Properties of Prostate Cancer Cells by Interfering with CD44 Variant Splicing

Supplementary Figure 5 - PDF file 104K, (A), mRNA levels of CD44v8-v10 (CD44v) were determined in human normal and prostate cancer tissues by RT-PCR. Normal, normal prostate tissue (n = 19); OC-PCa, organ-confined prostate cancer (n = 79); Met-PCa, metastatic prostate cancer (n = 23). (B), mRNA levels of CD44v were compared between patients with recurrent PCa (Rec, n = 44) and those without recurrent disease (Non-rec, n = 30). (C) and (D), mRNA levels of standard CD44 (CD44s) (C) or CD44v (D) were compared between patients with low grade PCa (Gleason score � 6, n = 21) and those with high grade disease (Gleason score > 6, n = 53). All experiments were repeated three times. Bars indicate median values