Figure S1 from Loss of FOXO1 Cooperates with TMPRSS2–ERG Overexpression to Promote Prostate Tumorigenesis and Cell Invasion

Yinhui Yang,Alexandra M. Blee,Dejie Wang,Jian An,Yunqian Pan,Yuqian Yan,Tao Ma,Yundong He, Joseph Dugdale, Xiaonan Hou,Jun Zhang,S. John Weroha,Wei-Guo Zhu,Y. Alan Wang,Ronald A. DePinho,Wanhai Xu,Haojie Huang

crossref（2023）

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摘要

Supplementary Figure S1. In panel A, ERG pull-down in HUVEC cells showing no interaction between FOXO1 and ERG. In contrast, AR binding with ERG is detected as expected. In panel B, bioinformatic analysis of 492 prostate cancer cases from TCGA to show the profiles of FOXO1, PTEN and ERG alterations. PTEN and FOXO1 deletions largely do not overlap.

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