Supplementary Figures 1-8 from M2 Macrophage-Derived Exosomes Promote Cell Migration and Invasion in Colon Cancer

Supplementary Figures 1-8： Supplementary Figure 1 Exosomes were produced by M2 macrophage. Supplementary Figure 2 M2-macrophage-derived exosomes enhance cell mobility, migration and invasion in SW480 and HCT 116 cells. Supplementary Figure 3 Increased miR-21-5p and miR-155-5p in exosomes and SW48 cells treated with exosomes derived from M2 macrophage. Supplementary Figure 4 BRG1 is the target of miR-21-5p and miR-155-5p Supplementary Figure 5 Downregulated BRG1 promote CRC cell migration and invasion. Supplementary Figure 6 BRG1 mediates CRC migration and invasion induced by M2 derived exosomes. Supplementary Figure 7 M2-macrophage-derived exosomes enhance cell migration and invasion in CO-115. Supplementary Figure 8 Quantification of relative protein level of BRG1 based on three independent tests for Fig. 6B.