Deciphering Dynamic Changes of the Aging Transcriptome with COVID-19 Progression and Convalescence in the Human Blood
Signal Transduction and Targeted Therapy(2023)
摘要
Dear Editor, Overwhelming evidence suggests that age itself is a prominent risk factor for COVID-19 morbidity and mortality.1,2 However,the molecular basis of aging's effect on SARS-CoV-2 susceptibility and COVID-19 severity in adults is still not fully understood.Thus,we hypothesized that aging-related cellular landscape alterations influence clinical manifestations,which is critical for determining likely intervention targets to slow the transmission of COVID-19 and reduce severe symptoms.
更多查看译文
关键词
Genome informatics,Infection,Medicine/Public Health,general,Internal Medicine,Cancer Research,Cell Biology,Pathology,Oncology
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要