Stability of the Inclusion Complexes of Dodecanoic Acid with -Cyclodextrin, -Cyclodextrin and 2-HP--Cyclodextrin

In the presented work, the stability of the formation of inclusion complexes of dodecanoic acid (lauric acid) with three cyclodextrins, alpha-cyclodextrin, beta-cyclodextrin and 2-HP-beta-cyclodextrin, was analyzed from the point of view of the size of the cavity in cyclodextrins, their molar mass and the structure of the studied fatty acid. The measurements were made in a wide temperature range of 283.15-318.15K. The conductometric method was used for these studies. The results obtained allowed us to determine the value of the theoretical limiting molar conductivity (Lambda(0)(m)) of the studied complexes, the values of the inclusion complex formation constants (K-f) and the values of thermodynamic functions (Delta G(0),Delta H-0 and Delta S-0) describing the complexation process in the studied temperature range.