Hemogenic activity of lymphatic endothelium unleashed

Nature Cardiovascular Research(2023)

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摘要
Specialized endothelial cells within certain embryonic blood vessels can generate hematopoietic cells. A recent study reveals blood-forming capacity also within embryonic lymphatic endothelium, which is suppressed during normal development by the lymphatic endothelial fate-determining transcription factor PROX1.
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关键词
lymphatic endothelium,hemogenic activity
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