Fabrication of Au Nanoparticles Coated Metal Fiber for the Solid-Phase Microextraction and Determination of Lamotrigine in Complex Matrixes

A solid phase microextraction fiber (SPME) with gold nanoparticles coatings (AuNPs) was prepared based on stainless-steel fiber by chemical deposition. In order to greatly increase the specific surface area of the stainless-steel fiber, the porous fiber were formed by hydrofluoric acid treatment and aqua regia-dopamine treatment after AuNPs coating. Thus, the porous gold coated SPME with large specific surface area, strong bonding and controllable thickness were prepared. Scanning electron microscopy (SEM) and elements analysis were used to characterize. Under the optimized conditions, the prepared fibers exhibited good precision, wide linear ranges, acceptable recoveries, and low limits of detection for lamotrigine. The results verified that this novel coating was a promising sorbent for extraction and trace analysis of lamotrigine in complex matrixes.