Comparison of the effects of exposure to nanosecond pulsed microwaves on a burn injury depending on the pulse repetition frequency

The effect of nanosecond repetitive pulsed microwaves (RPMs 10 GHz, 100 ns pulse duration, 8 and 13 Hz pulse repetition rate, 140 W/cm2 peak power flux density (pPFD)) on the regeneration of burn wounds in rats was studied. It is established that after 4-fold local irradiation of wounds with intensity of 140 W/cm2 at pulse repetition rates of 8 and 13 Hz stimulates the healing of burn wounds. A comparison of the obtained results allows us to state that nanosecond low-intensity RPMs of 140 W/cm2 accelerate wound healing processes. At the same time, the impact with a pulse repetition rate of 8 Hz turned out to be more effective in comparison with a pulse repetition frequency of 13 Hz. Histological analysis of rat skin showed an increase in the rate of wound healing due to the accelerated formation of granulation tissue, a decrease in the thickness of eschar and scarless healing.