Comparative computational study to augment UbiA prenyltransferases inherent in purple photosynthetic bacteria cultured from mangrove microbial mats in Qatar for coenzyme Q10 biosynthesis.

•PNSB could be inducted for industrial biosynthesis of vital antioxidant CoQ10.•Rate-limiting enzyme UbiA is crucial for efficacious biosynthesis of CoQ10.•Protein engineering conserved Asp-rich motifs could improve functionality of UbiA.•Plausible mutations and substitutions designated by comprehensive insilico study.•Interacting residue environment of engineered UbiA enzyme assessed by MLSD studies.