Critical Analysis Reveals Methodological Flaws in a Pilot Study Using Insurance Claims Data to Assess Cost Effectiveness of Prophylaxis Therapies for the Rare Disease Hereditary Angioedema (HAE)

Christian Jervelund, Nikolaj Siersbæk, Tony Castaldo,Christine Selva, Deborah Corcoran,Marc Riedl,Sandra Christiansen,Bruce Zuraw

Journal of Allergy and Clinical Immunology（2023）

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摘要

In a 2021 real-world evidence pilot study, the Institute for Clinical and Economic Research (ICER) concluded that long-term HAE prophylaxis (LTP) treatments are far less cost-effective than previously estimated. We assessed the accuracy of their methodologic analysis.

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rare disease hereditary angioedema,assess cost effectiveness,insurance,prophylaxis therapies

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