Abstract WP76: Death Rate And Risk Factors For Stroke Patients

Introduction: Stroke is a major contributor to emergency department (ED) cases and human mortality in the US. However, the annual trend in death rate and death risk factors in stroke has not been rigorously studied. Methods: We conducted a retrospective analysis of the Nationwide Emergency Department sample (NEDS). We analyzed incidence and death rate of stroke patients from 2006 to 2019. We used a multivariate logistic regression that included patient characteristics (e.g. age, Charlson Comorbidity Index, medication use) as covariates to identify death risk factors. Results: In this study time-period, 2,998,237 patients presented to the ED with a primary stroke. Stroke incidence increased by 39% from 1358 ± 56 to 1883 ± 69 per million US population (p<0.001) (Figure 1A). Total death rate decreased from 8.8% to 5.5% (p<0.001) (Figure 1B). This trend was mirrored in the admitted patients (9.7% to 6.8%, p<0.001) and non-admitted patients (1.71% to 0.65%, p<0.001) (Figure 1B). Death risk factors are displayed in Figure 2. Interestingly, being from the highest income quartile (OR: 1.15 ± 0.03, p<0.001) and a female (OR: 1.08 ± 0.02, p<0.001) are related to a higher risk of death. Interestingly, paying with private insurance is related with a lower risk of death (OR: 0.81 ± 0.03, p<0.001). Conclusion: In contrast to the increasing rise in stroke incidence, death rate is decreasing in both admitted and non-admitted patients. Furthermore, age, sex, and insurance status are related to a higher risk of death.