Front Cover: Unveiling the Collaborative Effect at the Cucurbit[8]uril‐MoS ₂ Hybrid Interface for Electrochemical Melatonin Determination (Chem. Eur. J. 9/2023)

An open-and-shut case: Cucurbit[8]uril adsorbs robustly on transition-metal dichalcogenides (TMDs) letting the cavity open for complex formation with melatonin and allowing efficient electrochemical sensing. This situation is reversed on graphene where the Cucurbit[8]uril's portals are closed, hindering the host–guest recognition. More information can be found in the Research Article by C. Quintana, J. A. Martín-Gago, and co-workers. (DOI: 10.1002/chem.202203244).