Material properties of human brain tissue suitable for modelling traumatic brain injury
Brain Multiphysics(2022)
摘要
•Significant neural cell death occurs in vitro when neural cells are exposed to a combination of strains ≥20% at strain rates ≥10/s.•Simulations of head impacts with clinically diagnosed TBIs found strains ≥14% at strain rates ≥20/s within the brain.•Only five studies in the literature have characterised the material properties of human brain tissue under strains ≥20% at strain rates ≥10/s.•There is a lack of material properties describing the mechanical behaviour of human brain tissue under conditions suitable for modelling TBI.
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关键词
Brain tissue,Mechanical characterisation,Traumatic brain injury,Injury threshold,Finite element,Neuron,Axon
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