O107 / #726 MIDLINE ISOLATION AND NEUROMONITORING WITH HIGH-DENSITY MICROELECTRODE ARRAYS FROM THE SURFACE OF THE SPINAL CORD

Intraoperative neuromonitoring (IONM) reduces the risk for postoperative neurological dysfunction during spinal cord surgery (1–4). Common IONM techniques do not record directly from the spinal cord, but instead rely on indirect measures, including evoked motor and sensory potentials. However, the exposed cord provides an untapped potential for direct assessment of function and pathology. Direct recordings from the spinal cord could lower the amount of stimulation required to capture responses and allow for continual monitoring (5–7). Here, we present results from human spinal cord recordings using highly conformable microelectrode arrays with high-density spatial coverage. Future clinical application of this technology would include treatment of spinal cord injury (SCI) and chronic pain.