Predictive value of early CTSI scores for early organ failure in patients with acute pancreatitis: a 5-year retrospective study from the emergency department of a large tertiary hospital

crossref(2022)

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摘要
Abstract Objective: Acute pancreatitis (AP) is a life-threatening disease frequently encountered in emergency rooms. We need to explore the significance of early CTSI score in patients with acute pancreatitis, especially in the assessment of organ failure. Methods: A total of 2828 AP patients between October 2013 to March 2019 were included in this study. We collected data such as age, sex, vital signs on admission (heart rate, systolic blood pressure, respiratory rate, GCS score), test data (creatinine, P/F), imaging content (pleural effusion, pancreatic necrosis score, Balthazar grades, CTSI score). We performed a retrospective analysis of the data. Results: AP patients who develop early organ failure have older age, faster heart rate, higher blood pressure and faster respiratory rate(P<0.001). If a pleural effusion is found on Computed Tomography (CT) examination, the patient may have organ failure. The mean CTSI score of AP patients with organ failure was 4.84, which was higher than that of patients without early organ failure. The area under the ROC curve of CTSI is 0.683, the cut-off is 3.5, the sensitivity is 68.3%, and the specificity is 61.5%. Conclusions: Vital signs of patients are closely related to organ failure. Early CTSI score is meaningful and has suggestive value for early organ failure. A routine CTSI score for patients with pancreatitis can help emergency physicians assess the condition.
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