Neuroprotective Effect of Sub-lethal Hyperthermia Preconditioning in a Rat Model of Repeated Closed Head Injury

Jing Xiong, Ying Lv,Xu Ma,Guangcong Peng,Chunyi Wu,Jun Hou,Yulan Zhang,Chongyun Wu,Timon Cheng-Yi Liu,Luodan Yang

Neuroscience（2023）

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摘要

•Hyperthermia preconditioning improves locomotor activity and anxiety-like behavior.•Hyperthermia preconditioning improves recognition and spatial memory.•Hyperthermia preconditioning inhibits rCHI-induced neuronal loss, injury, and apoptosis.•Hyperthermia preconditioning suppresses rCHI-induced excessive glial cells activation.

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关键词

hyperthermia,neuroprotective effect,head,sub-lethal

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