Emergence and Evolution of Unique Plasmids Harboring bla _IMP-70 and bla _CTX-M-253 in Multidrug-Resistant Providencia rettgeri

Although Providencia rettgeri is an opportunistic pathogen, its intrinsic resistance to colistin and tigecycline makes the treatment of carbapenem-resistant P. rettgeri challenging. We isolated a multidrug-resistant P. rettgeri strain which harbored a rare bla IMP variant, bla IMP-70 , a novel bla CTX-M variant, bla CTX-M-253 , and bla MOX-1 from a urinary sample obtained in Osaka, Japan.