COVID-19 can initiate and trigger henoch-schoenlein purpura; a case series

Abstract BackgroundAfter each peak of COVID-19 pandemic, an increase in post-COVID syndromes and long COVID-19 symptoms can be observed. Henoch-Schönlein purpura is an IgA-related vasculopathy involving small vessels, mostly in children.Case presentationthe first case was a 15-year-old boy who afflicted COVID-19 and after a while, he developed lower limb weakness, limping, abdominal pain, and proteinuria. In his kidney biopsy mesangioproliferation and IgA deposition in the mesangium were seen. The second case was a 15-year -old girl known case of Henoch-Schönlein purpura who experienced proteinuria and hematuria 10 days after COVID-19 affliction. In her kidney biopsy IgA deposition and hypercellular mesangium were found in favor of Henoch-Schönlein purpura flare up.ConclusionIt is postulated that COVID-19 can induce the first HSP flare up. It can also trigger HSP flare ups in patients with positive history of Henoch-Schoenlein Purpura.