Prediction of cardiovascular disease risk in patients with psoriasis in northern China

Abstract To investigate cardio vascular disease (CVD) risk factors and predict future CVD risk in patients with psoriasis in northern China, we conducted a retrospective study on risk factors in 1,067 psoriasis patients (psoriasis group) and 1,110 physical examiners without psoriasis (control group). Compared with the control group, the psoriasis group showed a stronger correlation with CVD history, body mass index, hypertension, diabetes mellitus, and dyslipidaemia (all P < 0.01). CVD was more common in patients with a long history of psoriasis (P < 0.01), and the incidence of severe psoriasis with diabetes was higher (P < 0.01). In the psoriasis prediction group, the proportion in psoriasis in the "medium risk" and "very high risk" was significantly higher (P < 0.01). Heart age was significantly increased than their actual in the "old people" (P < 0.01). The results showed that the risk factors for CVD in patients with psoriasis were higher than those in the control group, and psoriasis with a long history or severe disease had a higher risk of CVD. Patients with psoriasis have a higher risk of future CVD, and the predicted heart age in the older groups tends to exceed the actual age. This suggests that attention should be paid to the present and future risk of CVD in patients with psoriasis and to the management of cardiovascular comorbidities.