Performance Evaluation of Bimetallic Surface Plasmon Resonance Biosensor Based on Copper and MXene(Ti3C2Tx)

Abstract Copper having high electrical conductivity can be a candidate for the plasmonic metal. MXene (Ti3C2Tx) is an emerging two-dimensional material can be used in the biosensing field considering its excellent metallic conductivity and hydrophilic fictionalized surface terminations. Here, we employ copper and nickel as the plasmonic metals and MXene as the sensing interface to achieve significant improvement in sensitivity through angular interrogation. We propose three structures based on bimetallic materials of copper and nickel. Through systematic optimization of all parameters, three optimum sensing configurations from these structures have been achieved, where the highest sensitivity can be obtained is 626 º/RIU with 564% increment compared with that of pure copper-based sensor, and the limit of detection of the refractive index change can be as low as 1.5 × 10− 6 RIU.