Relation Between Height Loss and Cardiovascular Disease: Data From Large Korean Cohort

Abstract Question: What is the association between height loss and cardio-/cerebrovascular disease (CVD) incidence?Method: The data we obtained is a sample cohort data provided by NHIS from 2002 to 2015. The chi-square test and the Kruskal-Wallis test were used to see the group differences in demographic characteristics. To compute the primary and secondary outcomes, we used the Cox proportional-hazard model, Kaplan-Meier survival curve, and logistic regression.Results: The cumulative MACCE incidence rate was 3.6 % for Group 1, 4.5 % for Group 2, and 5.2 % for Group 3. Group 3 had a significantly higher incidence of MACCE than Group 1 (Group 1: hazard ratio [HR] = 1.46, 95 % confidence interval [CI] = 1.32-1.62; Group 2: HR = 1.27, 95 % CI = 1.17-1.37). In the model adjusted for age, sex, comorbidities, income level, body mass index, smoking, and drinking status, the MACCE risk was 1.25 times higher in Group 3 than Group 1 (95 % CI = 1.13-1.40).Conclusion: The degree of height loss was independently associated with CVD occurrences in the Korean population.