Phloroglucinol Derivatives with Α-Glucosidase Inhibitory Activities from Syzygium Fluviatile.

Four new phloroglucinol derivatives (1 - 4) were isolated from the leaves of Syzygium fluviatile. Their structures were elucidated by means of extensive spectroscopic data. Among them, compounds 1 and 3 showed significant inhibitory activity against alpha-glucosidase with IC50 values of 10.60 and 5.07 mu M, respectively. The structure-activity relationship was also discussed briefly. [GRAPHICS] .