Efficient reduction of quinoxaline compounds using zinc chloride—sodium borohydride system

Yuanguang Chen,Huashen Xu,Lu Chen,Yajie Shi,Anyuan Hou,Zhongbo Liu,Guoliang Chen

RUSSIAN CHEMICAL BULLETIN（2023）

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摘要

Reagent system NaBH 4 —ZnCl 2 was found to be suitable for the reduction of various substituted quinoxalines to obtain corresponding 1,2,3,4-tetrahydro derivatives. The reduction proceeds quickly under mild reaction conditions. The procedure is convenient and can be applied for a wide scope of substrates.

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关键词

quinoxaline compounds,chloride—sodium borohydride system,zinc chloride—sodium

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