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Cryptadine C, a New C27N3-type Lycopodium Alkaloid from Lycopodium Cryptomerinum

Yusuke Hirasawa,Rina Hattori, Manami Ohtani,Hiroshi Morita

Journal of Natural Medicines（2023）

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Abstract
A new C27N3-type Lycopodium alkaloid consisting of two decahydroquinolines and a piperidine, cryptadine C (1) was isolated from Lycopodium cryptomerinum. The structure and relative configuration of 1, which is related to those of cryptadines A and B, lycoperine A, and hupercumine A, was elucidated on the basis of spectroscopic data. Cryptadine C showed moderate inhibitory activity against acetylcholinesterase.
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Key words
Lycopodium alkaloid,Lycopodium cryptomerinum,Cryptadine C,Acetylcholinesterase
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