Genome-wide CRISPR/Cas9 screening identifies a targetable MEST-PURA interaction in cancer metastasis

Wen Wen Xu,Long Liao,Wei Dai,Can-Can Zheng,Xiang-Peng Tan,Yan He,Qi-Hua Zhang,Zhi-Hao Huang,Wen-You Chen,Yan-Ru Qin,Kui-Sheng Chen,Ming-Liang He,Simon Law,Maria Li Lung,Qing-Yu He,Bin Li

eBioMedicine（2023）

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摘要

This work was supported by National Key Research and Development Program of China (2021YFC2501000, 2021YFC2501900, 2017YFA0505100); National Natural Science Foundation of China (31961160727, 82073196, 81973339, 81803551); NSFC/RGC Joint Research Scheme (N_HKU727/19); Natural Science Foundation of Guangdong Province (2021A1515011158, 2021A0505030035); Key Laboratory of Guangdong Higher Education Institutes of China (2021KSYS009).

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关键词

crispr/cas9 screening,cancer,metastasis,genome-wide,mest-pura

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