Brain FDG-PET findings in chimeric antigen receptor T-cell therapy neurotoxicity for diffuse large B-cell lymphoma.

Silvia Morbelli,Massimiliano Gambella,Anna Maria Raiola,Chiara Ghiggi,Matteo Bauckneht,Tania Di Raimondo,Caterina Lapucci,Gianmario Sambuceti,Matilde Inglese,Emanuele Angelucci

JOURNAL OF NEUROIMAGING（2023）

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摘要

Patients with ICANS are characterized by a frontolateral hypometabolic signature coherently with the hypothesis of ICANS as a predominant frontal syndrome and with the more prominent susceptibility of frontal lobes to cytokine-induced inflammation.

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brain PET,CAR-T,lymphoma,neuroinflammation

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