Rab1A-Mediated Exosomal Sorting of miR-200c Enhances Breast Cancer Lung Metastasis.

Yuting Liu, Jie Tang,Xiaolan Qiu,Lucy A Teng,Mukesh K Sriwastva,Xuedong Han,Zhi Li,Minmin Liu, Shuangyue Liu, Dongzhu Da,Zhi Li,Linlin Zhen,Yi Ren

Breast cancer (Dove Medical Press)（2023）

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摘要

Our study has identified a novel molecular mechanism for breast cancer lung metastasis mediated by exosome cargo miRNAs and provided a new therapeutic strategy for cancer immunotherapy.

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关键词

extracellular vehicles,exosomes,breast cancer lung metastasis,miR-200c,Rab1A,miRNA sorting

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