Metal/covalent-organic framework-based biosensors for nucleic acid detection

Zi-Wei Yang,Jia-Jing Li,Yu-Han Wang, Fu-Han Gao, Jing-Lian Su,Yang Liu,Huai-Song Wang,Ya Ding

Coordination Chemistry Reviews（2023）

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摘要

•Advances of MOF/COF-based biosensors for nucleic acid detection.•Rational designing and effective regulation of MOF/COF-based biosensors for improving the sensitivity and specificity of nucleic acid detection.•Detection mechanisms of MOF/COF-based biosensors.•Prospects and challenges of MOFs/COFs in nucleic acid detection.

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关键词

Metal -organic frameworks, Covalent -organic frameworks, Nucleic acid testing, Rational design, Sensing and imaging

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