Synthesis of proposed structure of ledebourin A

Seunggyu Jeon,Seul Lee,Minkyu Ji,Md. Samsuzzaman,Sangil Kwon,Sun Yeou Kim,Seung-Yong Seo

Bioorganic & Medicinal Chemistry Letters（2023）

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摘要

•Total synthesis of C-prenylated homoisoflavonoid ledebourin A, isolated from Ledebouria floribundare.•The formation of 2,2-dimethylbenzopyran via [3,3]-σ rearrangement reaction.•The ability to recover from glyceraldehyde-induced cell death in Hep-G2 cells.

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关键词

Ledebourin A, 2-dimethylpyrano, Homoisoflavonoids, 3-benzylchromanone

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