Meta-analysis of Probiotics Combined with Pelyene Phosphatidylcholine in the Treatment of Nonalcoholic Fatty Liver Disease

Review question / Objective: What are the effects of probiotics combined with pelyene phosphatidylcholine in the treatment of nonalcoholic fatty liver disease?C o n d i t i o n b e i n g s t u d i e d : N o n a l c o h o l i c f a t t y l i v e r disease(NAFLD) is one of the most common chronic liver diseases in the world.NAFLD is characterized by a large spectrum of liver disease, from isolated steatosis to steatohepatitis, and can progress to cause hepatic fifibrosis formation and cirrhosis.In addition to existing drugs for the treatment of NAFLD, new therapeutic targets for NAFLD still need to be found.Existing studies have found that there is a relationship between NAFLD and gut microbiota dysbiosis (Mouzaki et al. 2019, Wigg et al. 2001, Zhu, L.et al.2013, Knight et al.2017).Probiotics have a certain effect on the treatment of NAFLD, but the single use of probiotics has a poor effect on the treatment of NAFLD.It is a worthy question to observe the efficacy of the combination of probiotics and polyene phosphatidylcholine in the treatment of NAFLD.