Meta-analysis of Bailing Capsule After Renal Transplantation

Abstract To objectively evaluate the effectivity and safety of Bailing Capsule After Renal Transplantation. Search Chinese Journal Full-text Database (CNKI), Chinese Science and Technology Periodical Full-text Database (VIP), Wanfang Database, PubMed, SCI, EMBase, The Cochrane Library database. Chinese uses "Bai Ling Capsule" "Kidney Transplant" as the search term, and English uses "Bailing Capsule","Bailing Jiaonang", "Corbrin Capsule", "CS-C-Q80", "Kidney transplant", "Renal transplant", etc. as search terms. Two people screened, extracted data, quality assessment and data analysis of the retrieved articles according to the inclusion criteria and exclusion criteria.A total of 10 studies were included, including 1580 patients. Meta analysis results:the experimental group was more effective than the control group in SCr level（ WMD = -28.40，95% CI： -45.87 ~ -10.94， Z = 3.19， P =0.001）、BUN levels（ WMD = -0.72，95% CI： -1.18 ~ -0.25， Z = 3.02， P =0.003）、 ALT levels( WMD = -6.05，95% CI：- 9.26 ~ -2.85， Z = 3.70， P = 0.0002）、AST levels（ WMD = -11.96，95% CI： -19.2 5~ -4.68， Z = 3.22， P = 0.001）.But the experimental group did not show significant effects in reducing the incidence of acute rejection.（ OR = 0.45，95% CI： 0.19 ~ 1.11， Z = 1.74， P =0.08）Compared with the control group, Bailing Capsule treatment group has obvious advantages in Improvement of liver and kidney function after renal transplantation1,but did not show good clinical results in reducing the incidence of acute rejection.