Downregulation of HHLA2 inhibits ovarian cancer progression via the NF-κB signaling pathway and suppresses the expression of CA9

Yuanyuan Fu, Panpan Zheng,Xiao Zheng, Lujun Chen,Caixia Kong, Wenzhi Liu, Shuping Li,Jingting Jiang

Cellular Immunology（2023）

引用 0|浏览6

暂无评分

摘要

•Downregulation of HHLA2 significantly suppressed the viability, invasion, and migration of OC cells.•The role of HHLA2 in malignant phenotypes of OC cells is dependent on NF-κB signaling and CA9.•Simultaneous downregulation of HHLA2 and overexpression of CA9 promote malignant phenotype of OC cells.•HHLA2 reduces the expression of CA9 via the NF-κB signaling pathway to inhibit OC progression.

查看译文

关键词

ovarian cancer progression,hhla2

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要