Cage-shaped silsesquioxane with multiactive sites for impeding aggregation of small insoluble organic molecule

Gang Wei,Yubin Yao,Hongbo Zhang,Wenguo Cui,Yong Lu

Chemical Engineering Journal（2023）

引用 0|浏览7

暂无评分

摘要

•POSS-SH with eight active sites was selected through density functional theory.•POSS-SH inhibit molecular aggregation by increasing molecular spacing to 8.063 Å.•This method has general applicability for increasing the effectiveness of drugs.

查看译文

关键词

Supermolecular cage,Insoluble drugs,Molecular aggregation,Solubility improvement,Drug efficacy

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要