TET2-Driver and NLRC4-Passenger Variants in Adult-Onset Autoinflammation

Ellen De Langhe,Sien Van Loo,Bert Malengier-Devlies,Mieke Metzemaekers,Frederik Staels,Jessica Vandenhaute,Nathalie Berghen,Raf Sciot,Anniek Corveleyn,Olga Tsuiko,Mieke Gouwy,Jan Lenaerts,Patrick Verschueren,Carine H. Wouters,Paul Proost,Patrick Matthys,Eric Legius,Rik Schrijvers

The New England journal of medicine（2023）

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摘要

Genetic Events in Adult-Onset Inflammatory Disease The case of a patient with adult-onset inflammatory disease is reported. Two somatic genetic events accounted for the disease and its onset in adulthood.

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adult-onset

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