367. A Computational Signature of Self-Other Mergence in Borderline Personality Disorder

Differentiating others’ mental states from one’s own is a prerequisite for flexible social interaction. Here we model a computation necessary to achieve this, namely agent-specific learning, wherein observations pertinent to Self and Other generate separate belief updates, allowing a subject to learn that others’ beliefs may differ from their own. We test a hypothesis that reduced agent-specificity in learning underpins relational instability in Borderline Personality Disorder (BPD).