S-1 maintenance therapy in Caucasian patients with metastatic esophagogastric adenocarcinoma–final results of the randomized AIO MATEO phase II trial

G. Stocker, S. Lorenzen, T. Ettrich, A.-L. Herz, F. Longo, A. Kiani, M. Venerito, J. Trojan, R. Mahlberg, N. Moosmann,B. Chibaudel, S. Kubicka,R. Greil, S. Daum, M. Geissler, J. Larcher-Senn, G. Keller,F. Lordick, G.M. Haag

ESMO Open（2023）

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摘要

•S-1 maintenance therapy was applied following 3 months induction chemotherapy.•S-1 maintenance leads to non-inferior overall survival compared with continued poly-chemotherapy.•Toxicity pattern favors S-1 maintenance therapy.

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