The interaction of an effector protein Hap secreted by Aeromonas salmonicida and myofibrillar protein of meat: Possible mechanisms from structural changes to sites of molecular docking

•The addition of Hap affects the structure and properties of MPs.•Hap could significantly degrade the MPs, with a focus on MHC and actin.•Hap has a typical catalytic active site of zinc-dependent metallopeptidase.•Hap binds to MPs through hydrophobic interaction and hydrogen bonding.