Tissue factor as a novel diagnostic target for early detection of ovarian cancer using ultrasound microbubbles
Gynecologic Oncology(2023)
摘要
•Identified that Tissue factor (TF) is uniquely expressed in ovarian tumor vasculature.•Developed a novel TF-targeting ultrasound microbubble for detection of early-stage OC.•Validated this TF-targeted microbubble using a clinically relevant OC mouse models.
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