Quantification of α-hydroxy ceramides in mice serum by LC-MS/MS: Application to sepsis study

Yufan Chao, Xiaoqing Chen,Xuan Shi,Na Li,Songyan Gao,Jingzhi Yang,Xin Dong

Journal of Chromatography B（2023）

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摘要

•Development of a sensitive and reliable LC-MS/MS method for the accurate quantification of six α-hydroxyl ceramides in serum.•Strong support for the research of biological function of α-hydroxyl ceramides in the future.•Revealing the α-hydroxyl ceramides associated with sepsis.

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关键词

α-hydroxy ceramides,LC-MS/MS,MRM,Sepsis,Serum

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